Precision under pressure series
Season 2: Precision under pressure
Season 2 - Precision under pressure: instantaneous wave-free ration (iFR) measurements and what matters
Season Introduction - Precision under pressure: instantaneous wave-free ratio (iFR) measurements and what matters
In this 6-episode season, you’ll explore the fundamentals of coronary physiology and learn how instantaneous wave-free ratio (iFR) supports confident decision-making in the cath lab. Compare iFR with FFR and other resting indices, review the clinical evidence and guideline support behind iFR, and understand how to integrate iFR into everyday workflow. You’ll also strengthen practical skills through troubleshooting strategies and real-world case examples that help ensure accurate measurements and reliable results.
Watch our teaser video to get a glimpse of what the series entails. For the full episode, create an account or login to get started.
Episode 1 - The pressure principle: The physiology that powers instantaneous wave-free ration (iFR)
In this episode, you’ll explore the core principles of coronary blood flow and pressure dynamics, including the roles of resistance, flow, and perfusion pressure. Learn how systolic and diastolic coronary flow differ and uncover the physiological basis of pressure-derived indices such as iFR. You’ll also see how these measurements help identify myocardial ischemia and support informed treatment decisions.
Watch our teaser video to get a glimpse of what the series entails. For the full episode, create an account or login to get started.
Episode 2 - No hyperemia, no problem: Exploring the benefits of iFR - comfort, speed, and clinical equivalence
In this episode, you’ll learn why iFR can be measured without pharmacologic hyperemia and explore the importance of the wave-free period in obtaining reliable results. Compare iFR with FFR to understand differences in patient comfort, procedural efficiency, and workflow. You’ll also review current guideline recommendations for coronary physiology and how iFR supports streamlined, evidence-based decision-making.
Watch our teaser video to get a glimpse of what the series entails. For the full episode, create an account or login to get started.
Episode 3: Pressure tested: The trials that shaped the guidelines
In this episode, you’ll review the landmark clinical trials that established the safety and efficacy of iFR, including DEFINE-FLAIR and iFR-SWEDEHEART. Explore the major findings related to outcomes such as major adverse cardiovascular events, revascularization rates, and patient comfort. You’ll also learn how these data influenced global guidelines and compare recommendations for iFR and FFR across leading cardiovascular societies.
Watch our teaser video to get a glimpse of what the series entails. For the full episode, create an account or login to get started.
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