Listen to Drs. Allen Jeremias, Gregg Stone, Habib Samady and Manesh Patel as they discuss the results of DEFINE PCI.
Is physiologic guidance the solution to residual ischemia?
A closer look at DEFINE PCI
The DEFINE PCI study used iFR pullback to understand the rate and causes of residual ischemia in 500 patients undergoing contemporary PCI. Early results find that residual ischemia is common, and causes are treatable.1
1 in 4 patients with residual ischemia
1 in 4 patients with angiographically successful PCI left the cath lab with residual ischemia.1
Mostly due to unseen focal lesion location
Of the patients with residual ischemia, 81.6% were caused by an untreated, angiographically inapparent physiologically focal stenosis of varying location.1
If all focal lesions had been successfully treated, only 4.9% of patients would remain with residual ischemia, a reduction of 79%.1
1. Jeremias A et al. The DEFINE PCI Trial: Blinded Physiological Assessment of Residual Ischemia after Successful Angiographic Percutaneous Coronary Intervention, presented at ACC 2019.
