The DEFINE PCI study used iFR pullback to understand the rate and causes of residual ischemia in 500 patients undergoing contemporary PCI. Early results find that residual ischemia is common, and causes are treatable.1
1 in 4 patients with residual ischemia
1 in 4 patients with angiographically successful PCI left the cath lab with residual ischemia.1
Mostly due to unseen focal lesion location
Of the patients with residual ischemia, 81.6% were caused by an untreated, angiographically inapparent physiologically focal stenosis of varying location.1
The findings from DEFINE PCI help support the value of using advanced physiologic guidance only offered by Philips to help decide not just whether to treat, but where to treat.
Without knowing the distribution of ischemia within the vessel, important segments can be missed and left untreated.
iFR Co-registration, from Philips, helps you:
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1. Jeremias A et al. The DEFINE PCI Trial: Blinded Physiological Assessment of Residual Ischemia after Successful Angiographic Percutaneous Coronary Intervention, presented at ACC 2019.